LIN28 inhibitor LI71
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
100mg | $2600 | To Be Confirmed |
200mg | $3900 | To Be Confirmed |
500mg | $6580 | To Be Confirmed |
Cat #: V33118 CAS #: 1357248-83-9 Purity ≥ 99%
Description: LIN28 inhibitor LI71 is a potent ,novel and cell-permeable LIN28 inhibitor, which abolishes LIN28-mediated oligouridylation with an IC50 of 7 uM.
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Molecular Weight (MW) | 335.40 |
---|---|
Molecular Formula | C21H21NO3 |
CAS No. | 1357248-83-9 |
SMILES Code | O=C(O)C1=CC=C([C@@H]2NC3=C(C=CC=C3OCC)[C@@]4([H])[C@]2([H])CC=C4)C=C1 |
Synonyms | LIN28 inhibitor LI71; L-I71; L I71; IUPAC/Chemical Name: 4-((3aS,4R,9bR)-6-ethoxy-3a,4,5,9b-tetra |
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 2.9815 mL | 14.9076 mL | 29.8151 mL | 59.6303 mL |
5mM | 0.5963 mL | 2.9815 mL | 5.9630 mL | 11.9261 mL |
10mM | 0.2982 mL | 1.4908 mL | 2.9815 mL | 5.9630 mL |
20mM | 0.1491 mL | 0.7454 mL | 1.4908 mL | 2.9815 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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Volume
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Molecular Weight*
The dilution calculator equation
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Volume(start)
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This equation is commonly abbreviated as: C1 V1 = C2 V2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.