Warfarin (WARF42; Athrombine-K)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
25g	$450	To Be Confirmed
50g	$650	To Be Confirmed
100g	$975	To Be Confirmed

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Cat #: V5301 CAS #: 81-81-2 Purity ≥ 98%

Description: Warfarin (WARF42; Athrombine-K; Coumadin) is a medication that is used as an anticoagulant in the prevention of thrombosis and thromboembolism, the formation of blood clots in the blood vessels and their migration elsewhere in the body, respectively.

References: Ansell, J., et al., Pharmacology and management of the vitamin K antagonists: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest, 2008. 133(6 Suppl): p. 160S-198S.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	308.33
Molecular Formula	C19H16O4
CAS No.	81-81-2
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
SMILES Code	CC(=O)CC(C1=C(O)c2ccccc2OC1=O)c3ccccc3
Synonyms	Dethmor; Dethnel; Dicusat E; NSC 59813; Panwarfin; Prothromadin; Arab Rat Death; Athrombine-K; BRN 1293536; BRN1293536; BRN-1293536; Brumolin; Caswell No. 903; CO-Rax; Compound 42; Coumadin; Coumafen; Coumafene; Coumaphene; Coumarins; Cov-R-Tox; d-Con;

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	3.2433 mL	16.2164 mL	32.4328 mL	64.8656 mL
5mM	0.6487 mL	3.2433 mL	6.4866 mL	12.9731 mL
10mM	0.3243 mL	1.6216 mL	3.2433 mL	6.4866 mL
20mM	0.1622 mL	0.8108 mL	1.6216 mL	3.2433 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.