UAMC-3203 HCl

This product is for research use only, not for human use. We do not sell to patients.

UAMC-3203 HCl
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$500Check With Us
500mg$880Check With Us
1g$1320Check With Us

Cat #: V4440 CAS #: 2271358-65-5 Purity ≥ 98%

Description: UAMC-3203 HCl (UAMC3203 hydrochloride) is a novel, potent, and selective Ferroptosis inhibitor (IC50 value =12 nM) with higher solublility and anti-inflammatory/antioxidant effects.

References: Devisscher L, et al. Discovery of Novel, Drug-Like Ferroptosis Inhibitors with in Vivo Efficacy. J Med Chem. 2018 Nov 21;61(22):10126-10140.

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Molecular Weight (MW)508.12
Molecular FormulaC25H38ClN5O2S
CAS No.2271358-65-5
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
SMILES CodeO=S(C1=CC=C(NC2CCCCC2)C(NCC3=CC=CC=C3)=C1)(NCCN4CCNCC4)=O.[H]Cl
SynonymsUAMC-3203; UAMC 3203; UAMC3203; UAMC-3203 HCl; UAMC-3203 hydrochloride;
ProtocolIn VivoNo toxicity is observed in mice after repeated injections of UAMC-3203 (20 µmol/kg; injected intraperitoneally; daily, over a period of 4 weeks).
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.9680 mL9.8402 mL19.6804 mL39.3608 mL
5mM0.3936 mL1.9680 mL3.9361 mL7.8722 mL
10mM0.1968 mL0.9840 mL1.9680 mL3.9361 mL
20mM0.0984 mL0.4920 mL0.9840 mL1.9680 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.