UAMC-3203

This product is for research use only, not for human use. We do not sell to patients.

UAMC-3203
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$2350To Be Confirmed
250mg$3650To Be Confirmed
500mg$5475To Be Confirmed

Cat #: V4269 CAS #: 2271358-64-4 Purity ≥ 98%

Description: UAMC-3203 (UAMC3203) is a novel and selective Ferroptosis inhibitor with an IC50 value of 12 nM.

References: Devisscher L, et al. Discovery of Novel, Drug-Like Ferroptosis Inhibitors with in Vivo Efficacy. J Med Chem. 2018 Nov 21;61(22):10126-10140.

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Product Promise

Promise
Molecular Weight (MW)471.66
Molecular FormulaC25H37N5O2S
CAS No.2271358-64-4
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
SMILES CodeO=S(C(C=C1NCC2=CC=CC=C2)=CC=C1NC3CCCCC3)(NCCN4CCNCC4)=O
SynonymsUAMC-3203 free base; UAMC-3203; UAMC 3203; UAMC3203;
ProtocolIn VivoNo toxicity is observed in mice after repeated injections of UAMC-3203 (20 µmol/kg; injected intraperitoneally; daily, over a period of 4 weeks).
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.1202 mL10.6009 mL21.2017 mL42.4034 mL
5mM0.4240 mL2.1202 mL4.2403 mL8.4807 mL
10mM0.2120 mL1.0601 mL2.1202 mL4.2403 mL
20mM0.1060 mL0.5300 mL1.0601 mL2.1202 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.