S107 hydrochloride

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
100mg	$572	Check With Us
200mg	$858	Check With Us
500mg	$1445	Check With Us

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Cat #: V33117 CAS #: 1357476-46-0 Purity ≥ 99%

Description: S107 hydrochloride is a novel, potent and RyR-selective 1,4-benzothiazepine analogue that stabilizes RyR2 channels by enhancing the binding affinity of calstabin2 to mutant and/or PKA-phosphorylated channels.

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Molecular Weight (MW)	245.77
Molecular Formula	C₁₁H₁₆ClNOS
CAS No.	1357476-46-0
SMILES Code	COC1=CC=C2SCCN(CC2=C1)C.Cl
Synonyms	S107 hydrochloride

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	4.0688 mL	20.3442 mL	40.6884 mL	81.3769 mL
5mM	0.8138 mL	4.0688 mL	8.1377 mL	16.2754 mL
10mM	0.4069 mL	2.0344 mL	4.0688 mL	8.1377 mL
20mM	0.2034 mL	1.0172 mL	2.0344 mL	4.0688 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.