UPGL00004
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $1550 | Check With Us |
| 250mg | $2580 | Check With Us |
| 500mg | $3870 | Check With Us |
: Cat #: V4103 CAS #: 1890169-95-5 Purity ≥ 98%
Description: UPGL00004 (UPGL-00004) is a novel, potent and allosteric inhibitor of glutaminase C (GAC, kidney glutaminase isoform C) with anticancer activity.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 534.66 |
|---|---|
| Molecular Formula | C25H26N8O2S2 |
| CAS No. | 1890169-95-5 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 25 mg/mLr |
| Water: N/Ar | |
| Ethanol: N/A | |
| SMILES Code | O=C(NC1=NN=C(N2CCC(NC3=NN=C(NC(CC4=CC=CC=C4)=O)S3)CC2)S1)CC5=CC=CC=C5 |
| Synonyms | UPGL00004; UPGL-00004; UPGL 00004 |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.8703 mL | 9.3517 mL | 18.7035 mL | 37.4070 mL |
| 5mM | 0.3741 mL | 1.8703 mL | 3.7407 mL | 7.4814 mL |
| 10mM | 0.1870 mL | 0.9352 mL | 1.8703 mL | 3.7407 mL |
| 20mM | 0.0935 mL | 0.4676 mL | 0.9352 mL | 1.8703 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.