Elbasvir
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $710 | Check With Us |
| 500mg | $1100 | Check With Us |
| 1g | $1650 | Check With Us |
: Cat #: V3702 CAS #: 1370468-36-2 Purity ≥ 98%
Description: Elbasvir (formerly known as MK-8742; MK8742; trade name Zepatier) is a potent NS5A (nonstructural protein 5A) inhibitor with anti-HCV (hepatitis C virus) activities against different HCV genotypes.
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- Physicochemical and Storage Information
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- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 882.02 |
|---|---|
| Molecular Formula | C49H55N9O7 |
| CAS No. | 1370468-36-2 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: >100 mg/mL (113.4 mM)r |
| Water: <1mg/mLr | |
| Ethanol:<1mg/mL | |
| SMILES Code | O=C(OC)N[C@H](C(N1[C@H](C2=NC(C3=CC=C4C(N5[C@H](C6=CC=CC=C6)OC4=C3)=CC7=C5C=CC(C8=CNC([C@H]9N(C([C@@H](NC(OC)=O)C(C)C)=O)CCC9)=N8)=C7)=CN2)CCC1)=O)C(C)C |
| Synonyms | MK8742; MK-8742; trade name Zepatier; MK 8742 |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.1338 mL | 5.6688 mL | 11.3376 mL | 22.6752 mL |
| 5mM | 0.2268 mL | 1.1338 mL | 2.2675 mL | 4.5350 mL |
| 10mM | 0.1134 mL | 0.5669 mL | 1.1338 mL | 2.2675 mL |
| 20mM | 0.0567 mL | 0.2834 mL | 0.5669 mL | 1.1338 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.