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Nafamostat Mesylate (FUT175)

This product is for research use only, not for human use. We do not sell to patients.

Nafamostat Mesylate (FUT175)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
2g$430Check With Us
5g$700Check With Us
10g$1050Check With Us

Cat #: V0707 CAS #: 82956-11-4 Purity ≥ 98%

Description: Nafamostat mesylate (formerly also known as FUT-175) is a novel and synthetic serine protease inhibitor, which is used as a short-acting anticoagulant during hemodialysis.

References: Ikehara S, et al. Effect of FUT-175, a new synthetic protease inhibitor, on the development of lupus nephritis in (NZB x NZW) F1 mice. Immunology. 1985 Aug;55(4):595-600.

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Product Promise

Promise
Molecular Weight (MW)539.58
Molecular FormulaC19H17N5O2.2CH4O3S
CAS No.82956-11-4
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 20 mg/mL (37.1 mM)r
Water: 53 mg/mL (98.2 mM)r
Ethanol: <1 mg/mL
SMILES CodeCS(=O)(O)=O.CS(=O)(O)=O.O=C(OC1=CC=C2C=C(C(N)=N)C=CC2=C1)C3=CC=C(NC(N)=N)C=C3
SynonymsFUT175; Nafamostat mesylate; FUT 175; FUT-175; nafamostat mesilate; .
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.8533 mL9.2665 mL18.5329 mL37.0659 mL
5mM0.3707 mL1.8533 mL3.7066 mL7.4132 mL
10mM0.1853 mL0.9266 mL1.8533 mL3.7066 mL
20mM0.0927 mL0.4633 mL0.9266 mL1.8533 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.