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BI-894999

This product is for research use only, not for human use. We do not sell to patients.

BI-894999
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1250Check With Us
500mg$1950Check With Us
1g$2925Check With Us
email: [email protected]        [email protected]

Cat #: V8789 CAS #: 1660117-38-3 Purity ≥ 99%

Description: BI-894999 is a novel, and selective BET inhibitor that has the potential to be used for the treatment of hematological malignancies by repression of super-enhancer driven oncogenes.

References: Harald Engelhardt, et al. Pyridinones. WO2015022332A1.

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Molecular Weight (MW)429.51
Molecular FormulaC25H27N5O2
CAS No.1660117-38-3
SMILES CodeCN1C(C(C)=CC(C2=NC3=CN=C(C4CCOCC4)C=C3N2[C@@H](C)C5=CC=CC=C5)=N1)=O <br/>
SynonymsBI-894999; BI894999; BI 894999
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.3282 mL11.6412 mL23.2823 mL46.5647 mL
5mM0.4656 mL2.3282 mL4.6565 mL9.3129 mL
10mM0.2328 mL1.1641 mL2.3282 mL4.6565 mL
20mM0.1164 mL0.5821 mL1.1641 mL2.3282 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.