Molibresib besylate
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $850 | To Be Confirmed |
| 200mg | $1275 | To Be Confirmed |
| 500mg | $2150 | To Be Confirmed |
: Cat #: V32069 CAS #: 1895049-20-3 Purity ≥ 99%
Description: Molibresib besylate (GSK-525762C; I-BET-762 besylate) is a novel and potent BET bromodomain inhibitor with IC50 of 32.5-42.5 nM and has immunomodulatory activity.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 582.07 |
|---|---|
| Molecular Formula | C28H28ClN5O5S |
| CAS No. | 1895049-20-3 |
| SMILES Code | O=C(NCC)C[C@H]1C2=NN=C(C)N2C3=CC=C(OC)C=C3C(C4=CC=C(Cl)C=C4)=N1.O=S(C5=CC=CC=C5)(O)=O |
| Synonyms | GSK525762A; GSK 525762A; IBET762; IBET762; IBET 762; molibresib; Molibresib besylate; GSK525762; GSK525762; GSK525762; GSK525762A; |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.7180 mL | 8.5900 mL | 17.1801 mL | 34.3601 mL |
| 5mM | 0.3436 mL | 1.7180 mL | 3.4360 mL | 6.8720 mL |
| 10mM | 0.1718 mL | 0.8590 mL | 1.7180 mL | 3.4360 mL |
| 20mM | 0.0859 mL | 0.4295 mL | 0.8590 mL | 1.7180 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.