N-Ethylmaleimide (NEM)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 10g | $1350 | In Stock |
| 50g | $2350 | In Stock |
| 100g | $3525 | In Stock |
: Cat #: V3163 CAS #: 128-53-0 Purity ≥ 98%
Description: N-Ethylmaleimide (also known as NEM) is an organic biochemical compound that is derived from maleic acid.
Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 125.13 |
|---|---|
| Molecular Formula | C6H7NO2 |
| CAS No. | 128-53-0 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: >25 mg/mL (199.8 mM)r |
| Water: >25 mg/mL (199.8 mM)r | |
| Ethanol: >25 mg/mL (199.8 mM) | |
| SMILES Code | C/C(C)=CCN1[C@@H](C)Cn2c3c(cccc3C1)[nH]c2=S |
| Synonyms | R-82150; R82150; R 82150; |
| Protocol | In Vitro | N-Ethylmaleimide (20 μM;30 min) inhibits Akt Ser-473, Akt Thr-308 , p70S6K, ribosomal protein S6, 4E-BP1, eIF4E, BAD and FKHR-L1 phosphorylation. |
|---|---|---|
| In Vivo | N-Ethylmaleimide (10 mg/kg; i.h.) promotes the prevalence situation of mice with acute gastric ulcers. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 7.9917 mL | 39.9584 mL | 79.9169 mL | 159.8338 mL |
| 5mM | 1.5983 mL | 7.9917 mL | 15.9834 mL | 31.9668 mL |
| 10mM | 0.7992 mL | 3.9958 mL | 7.9917 mL | 15.9834 mL |
| 20mM | 0.3996 mL | 1.9979 mL | 3.9958 mL | 7.9917 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.