BIX01338

This product is for research use only, not for human use. We do not sell to patients.

BIX01338
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$5500Check With Us
200mg$8250Check With Us
500mg$13900Check With Us

Cat #: V3454 CAS #: 1228184-65-3 Purity ≥ 98%

Description: BIX-01338 is a novel and potent histone lysine methyltransferase G9a inhibitor with an IC50 value of 4.7µM. BIX01338 was discovered by high-throughput screening along with BIX0129434.

References: Kubicek S, et al. Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase. Mol Cell. 2007 Feb 9;25(3):473-81.

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Product Promise

Promise
Molecular Weight (MW)621.56
Molecular FormulaC₃₂H₂₆F₃N₃O₇
CAS No.1228184-65-3
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
SMILES CodeO=C(O)C1=CC=C2C(N=C(N2CCC3=CC=C(C=C3)OC(C4=CC=C(C=C4)OC)=O)NC(C5=CC=C(C=C5)C(F)(F)F)=O)=C1.O
SynonymsBIX 01338 hydrate; BIX-01338 hydrate; BIX01338 hydrate;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.6089 mL8.0443 mL16.0886 mL32.1771 mL
5mM0.3218 mL1.6089 mL3.2177 mL6.4354 mL
10mM0.1609 mL0.8044 mL1.6089 mL3.2177 mL
20mM0.0804 mL0.4022 mL0.8044 mL1.6089 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.