SGC2085

This product is for research use only, not for human use. We do not sell to patients.

SGC2085
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$845Check With Us
500mg$1345Check With Us
1g$2015Check With Us

Cat #: V2763 CAS #: 1821908-48-8 Purity ≥ 98%

Description: SGC2085, identified from virtual screening approaches, is a novel, potent and selective inhibitor of coactivator associated arginine methyltransferase 1 (CARM1) with an IC50 of 50 nM.

References: Ferreira de Freitas R, et al. Discovery of a Potent and Selective Coactivator Associated Arginine Methyltransferase 1 (CARM1) Inhibitor by Virtual Screening. J Med Chem. 2016 Jul 28;59(14):6838-47.

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Product Promise

Promise
Molecular Weight (MW)312.41
Molecular FormulaC19H24N2O2
CAS No.1821908-48-8
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 62 mg/mL (198.45 mM)r
Water: <1 mg/mLr
Ethanol: 62 mg/mL (198.45 mM)
SMILES CodeC[C@H](N)C(NCC1=CC=C(OC2=CC(C)=CC(C)=C2)C(C)=C1)=O
SynonymsSGC2085; SGC-2085; SGC 2085
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.2009 mL16.0046 mL32.0092 mL64.0184 mL
5mM0.6402 mL3.2009 mL6.4018 mL12.8037 mL
10mM0.3201 mL1.6005 mL3.2009 mL6.4018 mL
20mM0.1600 mL0.8002 mL1.6005 mL3.2009 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.