DCLX069
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $515 | Check With Us |
| 200mg | $770 | Check With Us |
| 500mg | $1300 | Check With Us |
: Cat #: V19289 CAS #: 792946-69-1 Purity ≥ 99%
Description: DCLX069 (DCLX-069) is a novel, SAM-competitive and selective PRMT1 (protein arginine methyltransferase 1) inhibitor (IC50 =17.9 µM) with anticancer effects.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
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- Quality Control Documentation
| Molecular Weight (MW) | 339.43 |
|---|---|
| Molecular Formula | C20H25N3O2 |
| CAS No. | 792946-69-1 |
| Synonyms | DCLX 069; DCLX-069; DCLX069 |
| Protocol | In Vitro | DCLX069 (12.5-100 µM) effectively blocks cell proliferation in breast cancer, liver cancer and acute myeloid leukemia cell lines (MCF7, HepG2, and THP1 cells) in a concentration-dependent manner. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.9461 mL | 14.7306 mL | 29.4612 mL | 58.9223 mL |
| 5mM | 0.5892 mL | 2.9461 mL | 5.8922 mL | 11.7845 mL |
| 10mM | 0.2946 mL | 1.4731 mL | 2.9461 mL | 5.8922 mL |
| 20mM | 0.1473 mL | 0.7365 mL | 1.4731 mL | 2.9461 mL |
The molarity calculator equation
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The dilution calculator equation
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This equation is commonly abbreviated as: C1 V1 = C2 V2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.