CBB1007

This product is for research use only, not for human use. We do not sell to patients.

CBB1007
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$1100To Be Confirmed
200mg$1650To Be Confirmed
500mg$2780To Be Confirmed

Cat #: V17664 CAS #: 1379573-92-8 Purity ≥ 99%

Description: CBB-1007 is a novel and potent Lysine-specific demethylase 1 (LSD1) inhibitor (IC50 = 5.27 μM for hLSD1) with anticancer activity.

References: Wang J, et al. Novel histone demethylase LSD1 inhibitors selectively target cancer cells with pluripotent stem cell properties. Cancer Res. 2011 Dec 1;71(23):7238-49.

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Molecular Weight (MW)534.61
Molecular FormulaC27H34N8O4
CAS No.1379573-92-8
SMILES CodeO=C(OC)C1=CC(CN2CCN(C(N)=N)CC2)=CC(C(N3CCN(C(C4=CC=C(C(N)=N)C=C4)=O)CC3)=O)=C1
SynonymsCBB1007; CBB-1007; CBB 1007
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.8705 mL9.3526 mL18.7052 mL37.4104 mL
5mM0.3741 mL1.8705 mL3.7410 mL7.4821 mL
10mM0.1871 mL0.9353 mL1.8705 mL3.7410 mL
20mM0.0935 mL0.4676 mL0.9353 mL1.8705 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.