JAK1-IN-4

This product is for research use only, not for human use. We do not sell to patients.

JAK1-IN-4
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1650To Be Confirmed
500mg$2500To Be Confirmed
1g$3750To Be Confirmed

Cat #: V12079 CAS #: 2091134-35-7 Purity ≥ 99%

Description: JAK1-IN-4 is a novel and potent JAK1-selective kinase inhibitor with immunomodulatory effects.

References: Annika Birgitta Margareta ÅSTRAND, et al. Compounds and methods for inhibiting jak.

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Molecular Weight (MW)521.59
Molecular FormulaC26H32FN9O2
CAS No.2091134-35-7
SynonymsJAK1-IN-4
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.9172 mL9.5861 mL19.1721 mL38.3443 mL
5mM0.3834 mL1.9172 mL3.8344 mL7.6689 mL
10mM0.1917 mL0.9586 mL1.9172 mL3.8344 mL
20mM0.0959 mL0.4793 mL0.9586 mL1.9172 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.