UCB9608
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $750 | Check With Us |
| 250mg | $1250 | Check With Us |
| 500mg | $1875 | Check With Us |
: Cat #: V27783 CAS #: 1616413-96-7 Purity ≥ 99%
Description: UCB9608 is a Potent, orally Bioavailable PI4KIIIβ Inhibitor.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
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| Molecular Weight (MW) | 410.47 |
|---|---|
| Molecular Formula | C20H26N8O2 |
| CAS No. | 1616413-96-7 |
| SMILES Code | O=C(N1C[C@H](C)N(C2=C3C(N(C)N=C3)=NC(N)=N2)CC1)NC4=CC=C(OC)C=C4C |
| Synonyms | UCB9608; UCB-9608; UCB 9608 |
| Protocol | In Vitro | UCB9608 inhibits human mixed lymphocyte reaction, the IC50 is 37 nM. UCB9608 is a potent, selective and orally active PI4KIIIβ inhibitor, with an IC50 of 11 nM. UCB9608 is selective for PI4KIIIβ over PI3KC2 α, β, and γ lipid kinases. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.4362 mL | 12.1812 mL | 24.3623 mL | 48.7246 mL |
| 5mM | 0.4872 mL | 2.4362 mL | 4.8725 mL | 9.7449 mL |
| 10mM | 0.2436 mL | 1.2181 mL | 2.4362 mL | 4.8725 mL |
| 20mM | 0.1218 mL | 0.6091 mL | 1.2181 mL | 2.4362 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.