PS210

This product is for research use only, not for human use. We do not sell to patients.

PS210
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$680Check With Us
250mg$1300Check With Us
500mg$1950Check With Us

Cat #: V13313 CAS #: 1221962-86-2 Purity ≥ 99%

Description: PS210 (PS-210) is a novel and potent activator (in vitro) or inhibitor (in cells) of protein kinase PDK1 with anticancer activity.

References: Busschots K, et al. Substrate-selective inhibition of protein kinase PDK1 by small compounds that bind to the PIF-pocket allosteric docking site. Chem Biol. 2012 Sep 21;19(9):1152-63.

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Molecular Weight (MW)380.31
Molecular FormulaC19H15F3O5
CAS No.1221962-86-2
SMILES CodeO=C(O)C(C(C1=CC=CC=C1)CC(C2=CC=C(C(F)(F)F)C=C2)=O)C(O)=O 
SynonymsPS 210; PS-210; PS210
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.6294 mL13.1472 mL26.2943 mL52.5887 mL
5mM0.5259 mL2.6294 mL5.2589 mL10.5177 mL
10mM0.2629 mL1.3147 mL2.6294 mL5.2589 mL
20mM0.1315 mL0.6574 mL1.3147 mL2.6294 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.