Orlistat (Tetrahydrolipstatin)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 2g | $400 | In Stock |
| 5g | $680 | In Stock |
| 10g | $1020 | In Stock |
: Cat #: V2043 CAS #: 96829-58-2 Purity ≥ 98%
Description: Orlistat (also known as tetrahydrolipstatin, or Ro 18-0647, Lipase Inhibitor, THL ) is a potent and general lipase inhibitor with IC50 of 122 ng/ml for PL from human duodenal juice.
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- Physicochemical and Storage Information
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| Molecular Weight (MW) | 495.73 |
|---|---|
| Molecular Formula | C29H53NO5 |
| CAS No. | 96829-58-2 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 99 mg/mL (199.7 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: 99 mg/mL (199.7 mM) | |
| SMILES Code | CC(C)C[C@H](NC=O)C(O[C@@H](CCCCCCCCCCC)C[C@@H]([C@@H]1CCCCCC)OC1=O)=O |
| Synonyms | Ro 18-0647; Ro18-0647; Ro-18-0647; Ro 180647; Ro180647; Ro-180647; Alli, Tetrahydrolipastatin, Tetrahydrolipstatin, THLP, Xenical |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.0172 mL | 10.0861 mL | 20.1723 mL | 40.3445 mL |
| 5mM | 0.4034 mL | 2.0172 mL | 4.0345 mL | 8.0689 mL |
| 10mM | 0.2017 mL | 1.0086 mL | 2.0172 mL | 4.0345 mL |
| 20mM | 0.1009 mL | 0.5043 mL | 1.0086 mL | 2.0172 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.