TVB-3664

This product is for research use only, not for human use. We do not sell to patients.

TVB-3664
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$2350Check With Us
200mg$3525Check With Us
500mg$5950Check With Us

Cat #: V16948 CAS #: 2097262-58-1 Purity ≥ 99%

Description: TVB-3664 (TVB3664 ) is a novel and potent fatty acid synthase (FASN) inhibitor that is orally bioavailable, reversible, and selective.

References: Zaytseva YY, et al. Preclinical evaluation of novel fatty acid synthase inhibitors in primary colorectal cancer cells and a patient-derived xenograft model of colorectal cancer. Oncotarget. 2018 May 15;9(37):24787-24800.

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Product Promise

Promise
Molecular Weight (MW)468.47
Molecular FormulaC25H23F3N4O2
CAS No.2097262-58-1
SMILES CodeCC1=C(C2=C(COC)N=C(C(F)(F)F)N2)C=C(C(N3CC(C4=CC=C(C#N)C=C4)C3)=O)C(C)=C1
SynonymsTVB-3664; TVB 3664; TVB3664
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.1346 mL10.6730 mL21.3461 mL42.6922 mL
5mM0.4269 mL2.1346 mL4.2692 mL8.5384 mL
10mM0.2135 mL1.0673 mL2.1346 mL4.2692 mL
20mM0.1067 mL0.5337 mL1.0673 mL2.1346 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.