AZ-33

This product is for research use only, not for human use. We do not sell to patients.

AZ-33
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1250Check With Us
500mg$1950Check With Us
1g$2925Check With Us

Cat #: V12009 CAS #: 1370290-34-8 Purity ≥ 98%

Description: AZ-33, formerly known as LDHA Inhibitor 33, is a potent and novel LDHA (Lactate dehydrogenase A) inhibitor.

References: Ward RA,et al. Design and synthesis of novel lactate dehydrogenase A inhibitors by fragment-based lead generation. J Med Chem. 2012 Apr 12;55(7):3285-306. 

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Product Promise

Promise
Molecular Weight (MW)497.56
Molecular FormulaC25H27N3O6S
CAS No.1370290-34-8
SMILES CodeO=C(O)C(CC1=CC=C(CCCC(NCCC(NC2=CC=C3N=C(C)SC3=C2)=O)=O)C=C1)C(O)=O
SynonymsAZ-33; AZ 33; AZ33; LDHA Inhibitor 33
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.0098 mL10.0490 mL20.0981 mL40.1962 mL
5mM0.4020 mL2.0098 mL4.0196 mL8.0392 mL
10mM0.2010 mL1.0049 mL2.0098 mL4.0196 mL
20mM0.1005 mL0.5025 mL1.0049 mL2.0098 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.