Eflornithine HCl hydrate (DFMO; MDL71782; RMI71782)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 10g | $800 | Check With Us |
| 25g | $1350 | Check With Us |
| 50g | $2025 | Check With Us |
: Cat #: V17490 CAS #: 96020-91-6 Purity ≥ 98%
Description: Eflornithine HCl hydrate (DFMO; MDL71782; RMI71782; α-difluoromethylornithine) is a potent, specific, irreversible inhibitor of the enzyme ornithine decarboxylase.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
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- Quality Control Documentation
| Molecular Weight (MW) | 236.64 |
|---|---|
| Molecular Formula | C6H15ClF2N2O3 |
| CAS No. | 96020-91-6 |
| SMILES Code | NC(CCCN)(C(F)F)C(O)=O.[H]Cl.[H]O[H] |
| Synonyms | Eflornithine HCl hydrate; Eflornithine HCl; Eflornithine hydrochloride; Ornidyl.CPP-1X; RMI71782; RMI-71782; RMI 71782; DL-Ornithine hydrochloride; |
| Protocol | In Vivo | Eflornithine is the only new molecule registered for the treatment of human African trypanosomiasis over the last 50 years. It is the drug used mainly as a back-up for melarsoprol refractory Trypanosoma brucei gambiense cases. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 4.2258 mL | 21.1291 mL | 42.2583 mL | 84.5166 mL |
| 5mM | 0.8452 mL | 4.2258 mL | 8.4517 mL | 16.9033 mL |
| 10mM | 0.4226 mL | 2.1129 mL | 4.2258 mL | 8.4517 mL |
| 20mM | 0.2113 mL | 1.0565 mL | 2.1129 mL | 4.2258 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.