BX-912
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
250mg | $1150 | Check With Us |
500mg | $1750 | Check With Us |
1g | $2625 | Check With Us |
Cat #: V0236 CAS #: 702674-56-4 Purity ≥ 98%
Description: BX912 (BX-912) is a novel, potent and specific inhibitor of PDK-1 (phosphoinositide-dependent kinase 1) inhibitor with potential antitumor activity.
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Molecular Weight (MW) | 471.35 |
---|---|
Molecular Formula | C20H23BrN8O |
CAS No. | 702674-56-4 |
Shipping Temperature | -20℃ for 3 years in powder form -80℃ for 2 years in solvent |
Solubility In Vitro | DMSO: 94 mg/mL (199.4 mM)r |
Water: <1 mg/mLr | |
Ethanol: N/A | |
Solubility In Vivo | 30% PEG400+0.5% Tween80+5% propylene glycol: 30mg/mL |
SMILES Code | O=C(N1CCCC1)NC2=CC=CC(NC3=NC=C(Br)C(NCCC4=CNC=N4)=N3)=C2 |
Synonyms | BX 912; BX912; BX912 |
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 2.1216 mL | 10.6078 mL | 21.2157 mL | 42.4313 mL |
5mM | 0.4243 mL | 2.1216 mL | 4.2431 mL | 8.4863 mL |
10mM | 0.2122 mL | 1.0608 mL | 2.1216 mL | 4.2431 mL |
20mM | 0.1061 mL | 0.5304 mL | 1.0608 mL | 2.1216 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
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Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.