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TC-E 5003

This product is for research use only, not for human use. We do not sell to patients.

TC-E 5003
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
500mg$350Check With Us
1g$600Check With Us
5g$1520Check With Us
email: [email protected]        [email protected]

Cat #: V15915 CAS #: 17328-16-4 Purity ≥ 99%

Description: TC-E 5003 (TC-E5003) is a novel and potent protein arginine methyltransferase 1 (PRMT1) inhibitor with anticancer effects.

References: Bissinger EM, et al. Acyl derivatives of p-aminosulfonamides and dapsone as new inhibitors of the arginine methyltransferase hPRMT1. Bioorg Med Chem. 2011;19(12):3717-3731. 

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Molecular Weight (MW)401.26
Molecular FormulaC16H14Cl2N2O4S
CAS No.17328-16-4
SMILES CodeO=S(C1=CC=C(NC(CCl)=O)C=C1)(C2=CC=C(NC(CCl)=O)C=C2)=O
SynonymsTC-E 5003; TC E 5003; TCE 5003; TCE-5003; TCE5003;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.4921 mL12.4607 mL24.9215 mL49.8430 mL
5mM0.4984 mL2.4921 mL4.9843 mL9.9686 mL
10mM0.2492 mL1.2461 mL2.4921 mL4.9843 mL
20mM0.1246 mL0.6230 mL1.2461 mL2.4921 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.