Cintirorgon (LYC-55716)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
100mg | $1250 | In Stock |
250mg | $1950 | In Stock |
500mg | $2925 | In Stock |
Cat #: V3253 CAS #: 2055536-64-4 Purity ≥ 98%
Description: Cintirorgon (formerly also known as LYC55716; LYC-55716), a novel and potent immune modulatory medicine developed by Lycera, is a synthetic and orally bioavailable small molecule agonist of RAR-related orphan receptor γ (RORγ).
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Molecular Weight (MW) | 603.53 |
---|---|
Molecular Formula | C₂₇H₂₃F₆NO₆S |
CAS No. | 2055536-64-4 |
Storage | -20℃ for 3 years in powder formr |
-80℃ for 2 years in solvent | |
Solubility In Vitro | DMSO: > 10mMr |
Water: N/Ar | |
Ethanol: N/A | |
SMILES Code | O=C(O)C(C)(C)C[C@@H]1OC2=CC=C(C3=CC(F)=CC(OC(F)F)=C3)C=C2N(S(=O)(C4=CC=CC(C(F)(F)F)=C4)=O)C1 |
Synonyms | LYC-55716; Cintirorgon; LYC55716; LYC 55716 |
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 1.6569 mL | 8.2846 mL | 16.5692 mL | 33.1384 mL |
5mM | 0.3314 mL | 1.6569 mL | 3.3138 mL | 6.6277 mL |
10mM | 0.1657 mL | 0.8285 mL | 1.6569 mL | 3.3138 mL |
20mM | 0.0828 mL | 0.4142 mL | 0.8285 mL | 1.6569 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
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Volume(start)
=
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
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Volume(start)
V1
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Concentration(final)
C2
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V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.