Rubimaillin
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $400 | To Be Confirmed |
| 250mg | $800 | To Be Confirmed |
| 500mg | $1200 | To Be Confirmed |
: Cat #: V13996 CAS #: 55481-88-4 Purity ≥ 99%
Description: Rubimaillin (Mollugin) is a naturally occuring naphthohydroquinone extracted from Rubia cordifolia L. with anticancer activity.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
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| Molecular Weight (MW) | 284.31 |
|---|---|
| Molecular Formula | C17H16O4 |
| CAS No. | 55481-88-4 |
| SMILES Code | O=C(C1=C(C=CC(C)(C)O2)C2=C3C=CC=CC3=C1O)OC |
| Synonyms | Rubimaillin; Mollugin; |
| Protocol | In Vitro | Mollugin (0-80 μM, 12 h) enhances TNF-α-induced apoptosis. Mollugin (0-80 μM, 12 h) inhibits TNF-α-induced phosphorylation and nuclear translocation of p65, phosphorylation and degradation of IκBα, and IKK phosphorylation, and inhibits the TNF-α-induced mRNA expression of Cyclin D1, c-Myc, and VEGF. Mollugin (0-80 μM, 12 h) inhibits the proliferation of HeLa cells. Mollugin (0-80 μM, 24 h) inhibits the expression of an NF-κB reporter gene induced by TNF-α in a dose-dependent manner. |
|---|---|---|
| In Vivo | Mollugin (0-75 mg/kg, Orally, three times per week for 36 days) inhibits growth of HeLa cells in a xenograft tumor model. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.5173 mL | 17.5864 mL | 35.1729 mL | 70.3457 mL |
| 5mM | 0.7035 mL | 3.5173 mL | 7.0346 mL | 14.0691 mL |
| 10mM | 0.3517 mL | 1.7586 mL | 3.5173 mL | 7.0346 mL |
| 20mM | 0.1759 mL | 0.8793 mL | 1.7586 mL | 3.5173 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.