Sulbutiamine
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 50g | $400 | Check With Us |
| 100g | $650 | Check With Us |
| 200g | $975 | Check With Us |
: Cat #: V15446 CAS #: 3286-46-2 Purity ≥ 99%
Description: Sulbutiamine is a novel and potent antioxidant acting by inhibiting oxidative stress induced retinal ganglion cell death.
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| Molecular Weight (MW) | 702.89 |
|---|---|
| Molecular Formula | C32H46N8O6S2 |
| CAS No. | 3286-46-2 |
| SMILES Code | CC(C)C(OCC/C(SS/C(CCOC(C(C)C)=O)=C(N(CC1=CN=C(C)N=C1N)C=O)/C)=C(N(CC2=CN=C(C)N=C2N)C=O)C)=O |
| Synonyms | Sulbutiamine; Bisibuthiamine; Bisibutiamine; Arcalion; Vitaberin; |
| Protocol | In Vitro | Sulbutiamine shows neuroprotective effects on hippocampal CA1 pyramidal neurons subjected to oxygen-glucose deprivation. Sulbutiamine enhances electrophysiological properties such as excitatory synaptic transmissions and intrinsic neuronal membrane input resistance in a concentration-dependent manner. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.4227 mL | 7.1135 mL | 14.2270 mL | 28.4540 mL |
| 5mM | 0.2845 mL | 1.4227 mL | 2.8454 mL | 5.6908 mL |
| 10mM | 0.1423 mL | 0.7113 mL | 1.4227 mL | 2.8454 mL |
| 20mM | 0.0711 mL | 0.3557 mL | 0.7113 mL | 1.4227 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.