Menatetrenone (Vitamin MK4, E3100)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $550 | Check With Us |
| 1g | $850 | Check With Us |
| 5g | $2150 | Check With Us |
: Cat #: V25267 CAS #: 863-61-6 Purity ≥ 99%
Description: Menatetrenone (Vitamin MK-4, E-3100) is a menaquinone compound and a form of vitamin K2 with potential antineoplastic activity, used as a hemostatic agent, and also as adjunctive therapy for the pain of osteoporosis.
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| Molecular Weight (MW) | 444.65 |
|---|---|
| Molecular Formula | C31H40O2 |
| CAS No. | 863-61-6 |
| SMILES Code | O=C(C1=C2C=CC=C1)C(C/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)C)=C(C)C2=O |
| Synonyms | Menatetrenone; E-3100; Ea-0167; MK-4; Vitamin K-2(20); Vitamin MK-4; E 3100; Ea 0167; MK 4; Vitamin K 2(20); Vitamin MK 4; E3100; Ea0167; MK4; Vitamin K2(20); Vitamin MK4 |
| Protocol | In Vitro | Menaquinone-4 (MK-4, 0, 1, 5, 10 μM) increases the ALP activity in Caco-2 cells. Menaquinone-4 (1 μM) significantly increases intensities of hSI expression. |
|---|---|---|
| In Vivo | Menaquinone-4 (K2, 0.2 g/kg diet) in HF-K2 group produces epididymal fat in C57BL/6J mice, and also increases the bone density of mice. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.2490 mL | 11.2448 mL | 22.4896 mL | 44.9792 mL |
| 5mM | 0.4498 mL | 2.2490 mL | 4.4979 mL | 8.9958 mL |
| 10mM | 0.2249 mL | 1.1245 mL | 2.2490 mL | 4.4979 mL |
| 20mM | 0.1124 mL | 0.5622 mL | 1.1245 mL | 2.2490 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.