This product is for research use only, not for human use. We do not sell to patients.
| Size | Price | Stock |
|---|---|---|
| 250mg | $1650 | Check With Us |
| 500mg | $2280 | Check With Us |
| 1g | $3420 | Check With Us |
: Cat #: V3837 CAS #: 1047634-63-8 Purity ≥ 98%
Description: GSK2110183, an analog of Afuresertib, is a potent, orally bioavailable and ATP-competitive Akt inhibitor with Ki of 0.08 nM, 2 nM, and 2.6 nM for Akt1, Akt2, and Akt3, respectively.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 445.31 |
|---|---|
| Molecular Formula | C₁₈H₁₆Cl₂F₂N₄OS |
| CAS No. | 1047634-63-8 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 10 mMr |
| Water: <1 mg/mLr | |
| Ethanol: <1 mg/mL | |
| SMILES Code | O=C(C1=CC(C2=C(Cl)C=NN2C)=C(Cl)S1)N[C@@H](CC3=CC=C(F)C(F)=C3)CN |
| Synonyms | GSK 2110183-analog; Afuresertib-F free base; Afuresertib-F; GSK-2110183-analog; GSK2110183-analog; |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.2456 mL | 11.2281 mL | 22.4563 mL | 44.9125 mL |
| 5mM | 0.4491 mL | 2.2456 mL | 4.4913 mL | 8.9825 mL |
| 10mM | 0.2246 mL | 1.1228 mL | 2.2456 mL | 4.4913 mL |
| 20mM | 0.1123 mL | 0.5614 mL | 1.1228 mL | 2.2456 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.