Esculetin

This product is for research use only, not for human use. We do not sell to patients.

Esculetin
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
2g$300Check With Us
5g$450Check With Us
10g$675Check With Us

Cat #: V19575 CAS #: 305-01-1 Purity ≥ 98%

Description: Esculetin is a naturally occuring β-catenin inhibitor found mainly in chicory and other plant sources with antioxidant, antiinflammatory, and antitumor activities.

References: Xie C, et al. Esculetin regulates the phenotype switching of airway smooth muscle cells. Phytother Res. 2019 Aug 21.

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Product Promise

Promise
Molecular Weight (MW)178.14
Molecular FormulaC9H6O4
CAS No.305-01-1
SMILES Code O=C1C=CC2=CC(O)=C(O)C=C2O1
SynonymsNSC 26428; NSC-26428; NSC26428; Asculetine; CCRIS 7065; CCRIS-7065; CCRIS7065; Cichorigenin;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM5.6136 mL28.0678 mL56.1356 mL112.2712 mL
5mM1.1227 mL5.6136 mL11.2271 mL22.4542 mL
10mM0.5614 mL2.8068 mL5.6136 mL11.2271 mL
20mM0.2807 mL1.4034 mL2.8068 mL5.6136 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.