Hematein

This product is for research use only, not for human use. We do not sell to patients.

Hematein
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
10g$325Check With Us
25g$600Check With Us
50g$900Check With Us

Cat #: V15145 CAS #: 475-25-2 Purity ≥ 99%

Description: Hematein (Haematein) is a oxidized analogue of Hematoxylin used as a dye.

References: Shirai, K., & Matsuoka, M. (1996). Structure and properties of hematein derivatives. Dyes and Pigments, 32(3), 159–169.

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Molecular Weight (MW)300.26
Molecular FormulaC16H12O6
CAS No.475-25-2
SMILES Code O=C1C=C2CC3(O)C(C4=CC=C(O)C(O)=C4OC3)=C2C=C1O
SynonymsHematein, haematein, Hematoxylin, NSC 7333, NSC-7333, NSC7333, Haematoxylin, AI3-63013, AI3 63013, AI363013,
ProtocolIn VitroHematein (50 and 100 μM; 48 hours) inhibits CK2-specific Akt phosphorylation. Hematein (50 and 100 μM; 48 hours) induces apoptosis in A427 lung cancer cells. Hematein (10-100 μM; 14 days) inhibits cells growth in A427 lung cancer cells.
In VivoHematein (intraperitoneal injections; 50 mg/kg; twice a week for 6 weeks) inhibits tumor growth in A427 lung cancer cell xenografts.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.3304 mL16.6522 mL33.3045 mL66.6089 mL
5mM0.6661 mL3.3304 mL6.6609 mL13.3218 mL
10mM0.3330 mL1.6652 mL3.3304 mL6.6609 mL
20mM0.1665 mL0.8326 mL1.6652 mL3.3304 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.