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DMAT (CK2 Inhibitor; Casein kinase II Inhibitor)

This product is for research use only, not for human use. We do not sell to patients.

DMAT (CK2 Inhibitor; Casein kinase II Inhibitor)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$500Check With Us
250mg$950Check With Us
500mg$1425Check With Us

Cat #: V29439 CAS #: 749234-11-5 Purity ≥ 99%

Description: DMAT (CK2 Inhibitor; Casein kinase II Inhibitor) is a novel, potent and selective CK2 (Casein kinase II) inhibitor with an IC50 value of 130 nM.

References: Yde CW, et al. Induction of cell death in antiestrogen resistant human breast cancer cells by the protein kinase CK2 inhibitorDMAT. Cancer Lett. 2007 Oct 28;256(2):229-37.

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Molecular Weight (MW)476.79
Molecular FormulaC9H7Br4N3
CAS No.749234-11-5
SMILES CodeCN(C)C1=NC2=C(Br)C(Br)=C(Br)C(Br)=C2N1
SynonymsDMAT; 2dimethylamino4567tetrabromobenzimidazole
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.0974 mL10.4868 mL20.9736 mL41.9472 mL
5mM0.4195 mL2.0974 mL4.1947 mL8.3894 mL
10mM0.2097 mL1.0487 mL2.0974 mL4.1947 mL
20mM0.1049 mL0.5243 mL1.0487 mL2.0974 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.