NCC007
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $1250 | Check With Us |
| 1g | $1950 | Check With Us |
| 5g | $4935 | Check With Us |
: Cat #: V2584 CAS #: 2342583-66-6 Purity ≥ 99%
Description: NCC-007 is a novel and potent dual casein kinase Iα (CKIα) and δ (CKIδ) inhibitor.
Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 447.50 |
|---|---|
| Molecular Formula | C22H28F3N7 |
| CAS No. | 2342583-66-6 |
| SMILES Code | FC(C1=CC(CNC2=C3N=CN(C(C4CC4)C)C3=NC(NCCN(C)C)=N2)=CC=C1)(F)F |
| Synonyms | NCC007; NCC-007; NCC 007; |
| Protocol | In Vivo | NCC007 (5-15 mM, infused into the lateral ventricle) controls circadian rhythms through CKI inhibition. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.2346 mL | 11.1732 mL | 22.3464 mL | 44.6927 mL |
| 5mM | 0.4469 mL | 2.2346 mL | 4.4693 mL | 8.9385 mL |
| 10mM | 0.2235 mL | 1.1173 mL | 2.2346 mL | 4.4693 mL |
| 20mM | 0.1117 mL | 0.5587 mL | 1.1173 mL | 2.2346 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.