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BAY-218

This product is for research use only, not for human use. We do not sell to patients.

BAY-218
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1350Check With Us
500mg$1950Check With Us
1g$2925Check With Us
email: [email protected]        [email protected]

Cat #: V4433 CAS #: 2162982-11-6 Purity ≥ 98%

Description: BAY-218 (BAY218) is a novel, potent and selective small-molecule AhR (aryl hydrocarbon receptor) inhibitor with anticancer activities.

References: Norbert Schmees, et al. 3-oxo-2,6-diphenyl-2,3-dihydropyridazine-4-carboxamides. WO2017202816A1.

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Molecular Weight (MW)401.82
Molecular FormulaC20H17ClFN3O3
CAS No.2162982-11-6
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
SMILES CodeO=C(C1=CC(C2=CC=C(Cl)C=C2)=NN(C3=CC=CC(F)=C3)C1=O)N[C@@H](C)CO
SynonymsBAY-218; BAY 218; BAY218; BAY-2335218; BAY 2335218; BAY2335218;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.4887 mL12.4434 mL24.8868 mL49.7735 mL
5mM0.4977 mL2.4887 mL4.9774 mL9.9547 mL
10mM0.2489 mL1.2443 mL2.4887 mL4.9774 mL
20mM0.1244 mL0.6222 mL1.2443 mL2.4887 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
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Concentration
 
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Volume
 
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
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Volume(start)
V1
 
=
 
Concentration(final)
C2
 
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.