EMAC10101d
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $750 | Check With Us |
| 250mg | $1250 | Check With Us |
| 500mg | $1875 | Check With Us |
: Cat #: V2261 CAS #: 2561476-24-0 Purity ≥ 99%
Description: EMAC10101d bearing a 2,4-dichorophenyl substituent in position 4 of the dihydrothiazole ring, is a novel, potent and selective inhibitor of Carbonic Anhydrase Isoform toward hCA II.
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- Physicochemical and Storage Information
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- Related Biological Data
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| Molecular Weight (MW) | 428.36 |
|---|---|
| Molecular Formula | C17H15Cl2N3O2S2 |
| CAS No. | 2561476-24-0 |
| SMILES Code | O=S(C1=CC=C(/N=C2SC=C(C3=CC=C(Cl)C=C3Cl)N\2CC)C=C1)(N)=O |
| Synonyms | EMAC10101d; EMAC-10101d; EMAC 10101d |
| Protocol | In Vitro | EMAC10101d exhibits Ki values of 9627.4 nM, 8.1 nM, 224.6 nM and 154.9 nM for hCA Ⅰ, hCA II, hCAⅨ and hCA Ⅻ, respectively. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.3345 mL | 11.6724 mL | 23.3449 mL | 46.6897 mL |
| 5mM | 0.4669 mL | 2.3345 mL | 4.6690 mL | 9.3379 mL |
| 10mM | 0.2334 mL | 1.1672 mL | 2.3345 mL | 4.6690 mL |
| 20mM | 0.1167 mL | 0.5836 mL | 1.1672 mL | 2.3345 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
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Volume(start)
=
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
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V1
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C2
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V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.