Dichlorphenamide

This product is for research use only, not for human use. We do not sell to patients.

Dichlorphenamide
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
500mg$650Check With Us
1g$1050Check With Us
5g$2655Check With Us

Cat #: V0899 CAS #: 120-97-8 Purity ≥ 98%

Description: Dichlorphenamide (Daranide; Diclofenamide; Dichlofenamide) is a sulfonamide analog acting as a CAI/carbonic anhydrase inhibitor, it belongs to the meta-Disulfamoylbenzene class.

References: Kanski, J.J., Carbonic anhydrase inhibitors and osmotic agents in glaucoma. Carbonic anhydrase inhibitors. Br J Ophthalmol, 1968. 52(8): p. 642-3.

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Molecular Weight (MW)305.16
Molecular FormulaC6H6Cl2N2O4S2
CAS No.120-97-8
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 61 mg/mL (199.9 mM)r
Water: < 1 mg/mLr
Ethanol: 33 mg/mL (108.1 mM)
SMILES CodeC1=C(C=C(C(=C1S(=O)(=O)N)Cl)Cl)S(=O)(=O)N
SynonymsDaranide; Diclofenamide; Dichlorphenamide; Dichlofenamide; 4,5-dichlorobenzene-1,3-disulfonamide;
ProtocolIn VivoDichlorphenamide can reduce IOP locally in male albino rabbits.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.2770 mL16.3848 mL32.7697 mL65.5394 mL
5mM0.6554 mL3.2770 mL6.5539 mL13.1079 mL
10mM0.3277 mL1.6385 mL3.2770 mL6.5539 mL
20mM0.1638 mL0.8192 mL1.6385 mL3.2770 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.