Methocarbamol

This product is for research use only, not for human use. We do not sell to patients.

Methocarbamol
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Size Price Stock
25g$450Check With Us
50g$700Check With Us
100g$1050Check With Us

Cat #: V0897 CAS #: 532-03-6 Purity ≥ 99%

Description: Methocarbamol (Robaxin; AHR85; Lumirelax; AHR-85; Metocarbamolo), a carbamate analog of guaifenesin, is a potent carbonic anhydrase inhibitor (CAI) with sedative and musculoskeletal relaxant properties.

References: Bruce, R.B., L.B. Turnbull, and J.H. Newman, Metabolism of methocarbamol in the rat, dog, and human. J Pharm Sci, 1971. 60(1): p. 104-6.

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Molecular Weight (MW)241.24
Molecular FormulaC11H15NO5
CAS No.532-03-6
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 48 mg/mL (199.0 mM)r
Water: < 1 mg/mLr
Ethanol: 48 mg/mL (199.0 mM)
SMILES CodeCOC1=CC=CC=C1OCC(COC(=O)N)O
SynonymsAHR 85; Methocarbamol; Robaxin; Lumirelax; AHR-85; AHR85; Metocarbamolo
ProtocolIn VitroMethocarbamol (2 mM; for 20 min) significantly increases the decay times of the EPCs and those of the EPPs induced by the phrenic nerve stimulation.
In VivoMethocarbamol (200 mg/kg; ip) has Muscle relaxant activity of 88.96%.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM4.1452 mL20.7262 mL41.4525 mL82.9050 mL
5mM0.8290 mL4.1452 mL8.2905 mL16.5810 mL
10mM0.4145 mL2.0726 mL4.1452 mL8.2905 mL
20mM0.2073 mL1.0363 mL2.0726 mL4.1452 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.