Sennoside A

This product is for research use only, not for human use. We do not sell to patients.

Sennoside A
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
500mg$850Check With Us
1g$1350Check With Us
5g$3420Check With Us

Cat #: V0906 CAS #: 81-27-6 Purity ≥ 98%

Description: Sennoside A (formerly also known as NSC112929; NSC-112929), used as a laxative and an anti-constipation agent, is a naturally occurring dianthrone glycoside compound isolated from Rhei Rhizoma and senna leaf.

References: Rama Reddy NR, et al. Next Generation Sequencing and Transcriptome Analysis Predicts Biosynthetic Pathway of Sennosides from Senna (Cassia angustifolia Vahl.), a Non-Model Plant with Potent Laxative Properties. PLoS One. 2015 Jun 22;10(6):e0129422.

Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products

Product Promise

Promise
Molecular Weight (MW)862.74
Molecular FormulaC42H38O20
CAS No.81-27-6
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 125 mg/mLr
Water: N/Ar
Ethanol: N/A
SMILES CodeOC1C(O)C(OC2=C(C(C(C(O)=CC(C(O)=O)=C3)=C3C4C5C(C=CC=C6OC7C(O)C(O)C(O)C(CO)O7)=C6C(C8=C5C=C(C(O)=O)C=C8O)=O)=O)C4=CC=C2)OC(CO)C1
SynonymsNSC112929; NSC-112929; Sennoside A; NSC 112929;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.1591 mL5.7955 mL11.5910 mL23.1820 mL
5mM0.2318 mL1.1591 mL2.3182 mL4.6364 mL
10mM0.1159 mL0.5795 mL1.1591 mL2.3182 mL
20mM0.0580 mL0.2898 mL0.5795 mL1.1591 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.