PF-04929113 (SNX-5422)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $1450 | Check With Us |
| 500mg | $2080 | Check With Us |
| 1g | $3120 | Check With Us |
: Cat #: V0890 CAS #: 908115-27-5 Purity ≥ 98%
Description: PF-04929113 (SNX-5422; PF04929113; PF-4929113) is a potent and selective inhibitor of heat shock protein 90 (HSP90) with potential antineoplastic activity.
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- Physicochemical and Storage Information
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- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 521.53 |
|---|---|
| Molecular Formula | C25H30F3N5O4 |
| CAS No. | 908115-27-5 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 5 mg/mL (9.6 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: 3 mg/mL (5.2 mM) | |
| Solubility In Vivo | 0.5% CMC+0.25% Tween 80: 25mg/mL |
| SMILES Code | NCC(O[C@H]1CC[C@H](NC2=CC(N3N=C(C(F)(F)F)C4=C3CC(C)(C)CC4=O)=CC=C2C(N)=O)CC1)=O |
| Synonyms | SNX-5422; PF 4929113; PF04929113; PF 04929113; SNX5422; SNX 5422; PF-04929113; PF4929113; PF-4929113; |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.9174 mL | 9.5872 mL | 19.1744 mL | 38.3487 mL |
| 5mM | 0.3835 mL | 1.9174 mL | 3.8349 mL | 7.6697 mL |
| 10mM | 0.1917 mL | 0.9587 mL | 1.9174 mL | 3.8349 mL |
| 20mM | 0.0959 mL | 0.4794 mL | 0.9587 mL | 1.9174 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.