FIPI

This product is for research use only, not for human use. We do not sell to patients.

FIPI
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1050Check With Us
500mg$1650Check With Us
1g$2475Check With Us
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Product Promise

Promise
Molecular Weight (MW)421.47
Molecular FormulaC23H24FN5O2
CAS No.939055-18-2
SMILES CodeFIPI free base, FIPI; 5-Fluoro-2-indolyl des-chlorohalopemide;
SynonymsO=C(C(N1)=CC2=C1C=CC(F)=C2)NCCN3CCC(N(C4=CC=CC=C4N5)C5=O)CC3
ProtocolIn VivoDespite the high clearance of greater than 2 L/h/kg, FIPI shows a half-life of greater than 5 h, a Cmax of greater than 10-fold the 50 versus PLD2, and moderate bioavailability of 18%.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.3726 mL11.8632 mL23.7265 mL47.4530 mL
5mM0.4745 mL2.3726 mL4.7453 mL9.4906 mL
10mM0.2373 mL1.1863 mL2.3726 mL4.7453 mL
20mM0.1186 mL0.5932 mL1.1863 mL2.3726 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.