Nicotiflorin

This product is for research use only, not for human use. We do not sell to patients.

Nicotiflorin
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Size Price Stock
100mg$1100Check With Us
200mg$1650Check With Us
500mg$2785Check With Us

Cat #: V32275 CAS #: 17650-84-9 Purity ≥ 99%

Description: Nicotiflorin is a novel and potent flavonoid glycoside extracted from Chinese medicine Carthamus tinctorius.

References: Lal Shyaula S, et al. Synthesis and antiglycation activity of kaempferol-3-O-rutinoside (nicotiflorin). Med Chem. 2012 May;8(3):415-20.

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Molecular Weight (MW)594.52
Molecular FormulaC27H30O15
CAS No.17650-84-9
SynonymsNicotiflorin
ProtocolIn VitroFor primarily cultured neurons suffered 2 h hypoxia followed by 24 h reoxygenation, nicotiflorin significantly attenuates cell death and reduces LDH release. Morphological observation also directly confirms its protective effect on neuron.
In VivoAt doses of 2.5, 5 and 10 mg/kg, nicotiflorin administered immediately after the onset of ischemia markedly reduces brain infarct volume and neurological deficits.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.6820 mL8.4101 mL16.8203 mL33.6406 mL
5mM0.3364 mL1.6820 mL3.3641 mL6.7281 mL
10mM0.1682 mL0.8410 mL1.6820 mL3.3641 mL
20mM0.0841 mL0.4205 mL0.8410 mL1.6820 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.