Naringin
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 5g | $95 | Check With Us |
| 10g | $130 | Check With Us |
| 20g | $195 | Check With Us |
: Cat #: V0823 CAS #: 10236-47-2 Purity ≥ 99%
Description: Naringin (also known as Naringoside; AI319008; Aurantiin; AI3-19008), a flavanone-7-O-glycoside, is a novel, potent, natural flavanone glycoside found in citrus fruits (e.g. tomatoes and grapefruits).
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 580.53 |
|---|---|
| Molecular Formula | C27H32O14 |
| CAS No. | 10236-47-2 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 116 mg/mL (199.8 mM)r |
| Water: 2 mg/mL (9.1 mM)r | |
| Ethanol: 2 mg/mL (3.4 mM) | |
| SMILES Code | O=C1CC(C2=CC=C(O)C=C2)OC3=C1C(O)=CC(O[C@H]4[C@@H]([C@H]([C@@H]([C@@H](CO)O4)O)O)O[C@H]5[C@@H]([C@@H]([C@H]([C@H](C)O5)O)O)O)=C3 |
| Synonyms | Naringoside; AI319008; Aurantiin; AI3-19008; AI3 19008; Naringin |
| Protocol | In Vitro | Naringin suppresses NF-κ B signaling pathway activation. Naringenin inhibits high glucose-induced proliferation, inflammatory reaction and oxidative stress injury in HBZY-1 cells. |
|---|---|---|
| In Vivo | Treatment with naringin significantly alleviates renal injury in diabetic rats and increases diabetic rats body weight significantly. Administration of naringin effectively alleviates the collagen deposition and renal interstitial fibrosis in diabetic rats. Treatment with naringin could result in decreased levels of ROS and MDA and increased activities of SOD and GSH-Px. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.7226 mL | 8.6128 mL | 17.2256 mL | 34.4513 mL |
| 5mM | 0.3445 mL | 1.7226 mL | 3.4451 mL | 6.8903 mL |
| 10mM | 0.1723 mL | 0.8613 mL | 1.7226 mL | 3.4451 mL |
| 20mM | 0.0861 mL | 0.4306 mL | 0.8613 mL | 1.7226 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.