E3 ligase Ligand 1
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $380 | Check With Us |
| 500mg | $550 | Check With Us |
| 1g | $825 | Check With Us |
: Cat #: V3588 CAS #: 1948273-03-7 Purity ≥ 98%
Description: E3 ligase Ligand 1 is a novel, potent and selective ligand for E3 Ligase used in PROTAC technology.
References: WO/2017/030814A1
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- Physicochemical and Storage Information
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- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 481.05 |
|---|---|
| Molecular Formula | C₂₃H₃₃ClN₄O₃S |
| CAS No. | 1948273-03-7 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| SMILES Code | N[C@@H](C(C)(C)C)C(N1[C@H](C(N[C@@H](C)C2=CC=C(C3=C(C)N=CS3)C=C2)=O)C[C@@H](O)C1)=O.Cl |
| Synonyms | E3 ligase Ligand-1; E3 ligase Ligand1; E3 ligase Ligand 1 |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.0788 mL | 10.3939 mL | 20.7879 mL | 41.5757 mL |
| 5mM | 0.4158 mL | 2.0788 mL | 4.1576 mL | 8.3151 mL |
| 10mM | 0.2079 mL | 1.0394 mL | 2.0788 mL | 4.1576 mL |
| 20mM | 0.1039 mL | 0.5197 mL | 1.0394 mL | 2.0788 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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The dilution calculator equation
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Volume(start)
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This equation is commonly abbreviated as: C1 V1 = C2 V2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.