E3 ligase Ligand 4
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 2g | $450 | Check With Us |
| 5g | $750 | Check With Us |
| 10g | $1125 | Check With Us |
: Cat #: V3591 CAS #: 835616-60-9 Purity ≥ 98%
Description: E3 ligase Ligand, a fluoronated thalidomide, is a CRBN ligand for E3 Ligase used in PROTAC technology.
Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 276.22 |
|---|---|
| Molecular Formula | C₁₃H₉FN₂O₄ |
| CAS No. | 835616-60-9 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| SMILES Code | O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3F)=O |
| Synonyms | TC E3 5032; TC E35032; TC E3-5032; TCE3 5032; TCE35032; TCE3-5032; 4-Fluoro-thalidomide; |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.6203 mL | 18.1015 mL | 36.2030 mL | 72.4061 mL |
| 5mM | 0.7241 mL | 3.6203 mL | 7.2406 mL | 14.4812 mL |
| 10mM | 0.3620 mL | 1.8102 mL | 3.6203 mL | 7.2406 mL |
| 20mM | 0.1810 mL | 0.9051 mL | 1.8102 mL | 3.6203 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.