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Biotin-PEG7-amine

This product is for research use only, not for human use. We do not sell to patients.

Biotin-PEG7-amine
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$850Check With Us
500mg$1100Check With Us
1g$1650Check With Us

Cat #: V8152 CAS #: 1334172-76-7 Purity ≥ 98%

Description: Biotin-PEG7-amine is PEG analogue containing a biotin group and a terminal primary amine group.

References: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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Product Promise

Promise
Molecular Weight (MW)594.76
Molecular FormulaC26H50N4O9S
CAS No.1334172-76-7
SMILES CodeO=C1N[C@@]2([H])CS[C@@H](CCCCC(NCCOCCOCCOCCOCCOCCOCCOCCN)=O)[C@@]2([H])N
SynonymsBiotin-PEG7-amine
ProtocolIn VitroPROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.6814 mL8.4068 mL16.8135 mL33.6270 mL
5mM0.3363 mL1.6814 mL3.3627 mL6.7254 mL
10mM0.1681 mL0.8407 mL1.6814 mL3.3627 mL
20mM0.0841 mL0.4203 mL0.8407 mL1.6814 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.