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Tos-PEG4-t-butyl ester

This product is for research use only, not for human use. We do not sell to patients.

Tos-PEG4-t-butyl ester
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
500mg$600Check With Us
1g$850Check With Us
5g$2150Check With Us

Cat #: V16616 CAS #: 217817-01-1 Purity ≥ 98%

Description: Tos-PEG4-t-butyl ester is a PEG analogue containing a t-butyl ester and a tosyl group.

References: Popow J, et al. Highly Selective PTK2 Proteolysis Targeting Chimeras to Probe Focal Adhesion Kinase Scaffolding Functions. J Med Chem. 2019 Mar 14;62(5):2508-2520.

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Product Promise

Promise
Molecular Weight (MW)432.53
Molecular FormulaC20H32O8S
CAS No.217817-01-1
SMILES CodeO=S(C1=CC=C(C)C=C1)(OCCOCCOCCOCCC(OC(C)(C)C)=O)=O
SynonymsTos-PEG4-t-butyl ester
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.3120 mL11.5599 mL23.1198 mL46.2396 mL
5mM0.4624 mL2.3120 mL4.6240 mL9.2479 mL
10mM0.2312 mL1.1560 mL2.3120 mL4.6240 mL
20mM0.1156 mL0.5780 mL1.1560 mL2.3120 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.