7-Epi 10-desacetyl paclitaxel
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $850 | Check With Us |
| 250mg | $1500 | Check With Us |
| 500mg | $2250 | Check With Us |
: Cat #: V29320 CAS #: 78454-17-8 Purity ≥ 99%
Description: 7-Epi 10-desacetyl paclitaxel is a taxol analog and impurity of paclitaxel (Taxol), which is a microtubule polymer stabilizer (tubulin inhibitor) and chemotherapeutic drug used for the treatment of a wide variety of cancers.
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| Molecular Weight (MW) | 811.87 |
|---|---|
| Molecular Formula | C45H49NO13 |
| CAS No. | 78454-17-8 |
| SMILES Code | C[C@@]1([C@@]([H])([C@@](CO2)(OC(C)=O)[C@]2(C[C@H]1O)[H])[C@@H]3OC(C4=CC=CC=C4)=O)C([C@H](O)C5=C([C@H](C[C@@]3(C5(C)C)O)OC([C@@H]([C@@H](NC(C6=CC=CC=C6)=O)C7=CC=CC=C7)O)=O)C)=O |
| Synonyms | Ormosin VI; 10-Deacetyl-7-epitaxol; 10-Deacetyl-7-epi-10-deacetyl Paclitaxel; 7-epi-10-Deacetyltaxol; 7-epi-paclitaxel; 10-Deacetyl-7-epipaclitaxel; 10-Desacetyl-7-epi-taxol; 10-Desacetyl-7-epipaclitaxel; |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.2317 mL | 6.1586 mL | 12.3172 mL | 24.6345 mL |
| 5mM | 0.2463 mL | 1.2317 mL | 2.4634 mL | 4.9269 mL |
| 10mM | 0.1232 mL | 0.6159 mL | 1.2317 mL | 2.4634 mL |
| 20mM | 0.0616 mL | 0.3079 mL | 0.6159 mL | 1.2317 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.