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Wilforlide A (Regelide; Abruslactone A)

This product is for research use only, not for human use. We do not sell to patients.

Wilforlide A (Regelide; Abruslactone A)
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Size Price Stock
250mg$1240Check With Us
500mg$1750Check With Us
1g$2625Check With Us

Cat #: V5097 CAS #: 84104-71-2 Purity ≥ 99%

Description: Wilforlide A (also known as Regelide and Abruslactone A) is a natural product isolated from the ethanolic extract of tripterygium wilfordii.

References: Mei Xue, et al. Comparative study on the anti-inflammatory and immune suppressive effect of Wilforlide A. Fitoterapia

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Molecular Weight (MW)454.68
Molecular FormulaC30H46O3
CAS No.84104-71-2
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
SMILES CodeO=C1[C@@](C2)(C)C[C@]3([H])[C@](CC[C@@]4(C)[C@]5(C)CC[C@@]6([H])C(C)(C)[C@@H](O)CC[C@]6(C)[C@@]5([H])CC=C43)(C)[C@@]2([H])O1
SynonymsAbruslactone A; Wilforlide A; Regelide;
ProtocolIn VivoWilforlide A (30-150 μg/kg) markedly inhibits rat granulation induced by tampon. Wilforlide A (60-300 μg/kg) markedly inhibits mice auricular swelling induced by dimethylbenzene in ICR mice. Wilforlide A exhibits inhibition rates with 50.9% and 12.29% for high dose and low dose Wilforlide A, resepectively.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.1993 mL10.9967 mL21.9935 mL43.9870 mL
5mM0.4399 mL2.1993 mL4.3987 mL8.7974 mL
10mM0.2199 mL1.0997 mL2.1993 mL4.3987 mL
20mM0.1100 mL0.5498 mL1.0997 mL2.1993 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.