4-Methylumbelliferone (Hymecromone; 4-MU)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
10g | $250 | Check With Us |
50g | $700 | Check With Us |
100g | $1050 | Check With Us |
Cat #: V1976 CAS #: 90-33-5 Purity ≥ 98%
Description: 4-Methylumbelliferone (Hymecromone; 4-MU) is a potent and selective inhibitor of hyaluronic acid (HA) biosynthesis with an IC50 of 0.4 mM.
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Molecular Weight (MW) | 176.17 |
---|---|
Molecular Formula | C10H8O3 |
CAS No. | 90-33-5 |
Storage | -20℃ for 3 years in powder formr |
-80℃ for 2 years in solvent | |
Solubility In Vitro | DMSO: 35 mg/mL (198.7 mM)r |
Water: <1 mg/mLr | |
Ethanol: 35 mg/mL (198.7 mM) | |
SMILES Code | O=C1C=C(C)C2=C(O1)C=C(O)C=C2 |
Synonyms | Hymecromone; 4-MU; 4MU; 4 MU |
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 5.6763 mL | 28.3817 mL | 56.7634 mL | 113.5267 mL |
5mM | 1.1353 mL | 5.6763 mL | 11.3527 mL | 22.7053 mL |
10mM | 0.5676 mL | 2.8382 mL | 5.6763 mL | 11.3527 mL |
20mM | 0.2838 mL | 1.4191 mL | 2.8382 mL | 5.6763 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.