Nafamostat (FUT-175)

This product is for research use only, not for human use. We do not sell to patients.

Nafamostat (FUT-175)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
500mg$420To Be Confirmed
1g$700To Be Confirmed
5g$1770To Be Confirmed

Cat #: V29216 CAS #: 81525-10-2 Purity ≥ 98%

Description: Nafamostat (formerly also known as FUT-175) is a novel and synthetic serine protease inhibitor, which is used as an anticoagulant during hemodialysis.

References: Ikehara S, et al. Effect of FUT-175, a new synthetic protease inhibitor, on the development of lupus nephritis in (NZB x NZW) F1 mice. Immunology. 1985 Aug;55(4):595-600.

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Product Promise

Promise
Molecular Weight (MW)347.37
Molecular FormulaC19H17N5O2
CAS No.81525-10-2
SMILES CodeO=C(OC1=CC=C2C=C(C(N)=N)C=CC2=C1)C3=CC=C(NC(N)=N)C=C3
SynonymsNafamostat
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.8788 mL14.3939 mL28.7877 mL57.5755 mL
5mM0.5758 mL2.8788 mL5.7575 mL11.5151 mL
10mM0.2879 mL1.4394 mL2.8788 mL5.7575 mL
20mM0.1439 mL0.7197 mL1.4394 mL2.8788 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.